Orthosiphon stamineus is a herb that is widely grown in tropical areas. Nov 08, 2015 the aim of the study was to explore a propriety standardized ethanolic extract from leaves of orthosiphon stamineus benth in improving impairments in shortterm social memory in vivo, possibly via blockade of adenosine a2a receptors a2ar. Online plant guide orthosiphon stamineus cats whiskers. Oct 15, 2010 extracts of the orthosiphon stamineus plant were tested for antimicrobial and antioxidant activities against selected foodborne bacteria in vitro. Antihyperuricemic and nephroprotective effects of extracts. Orthosiphon aristatus or java tea grow herbal remedy in. Frontiers ethanolic extract of orthosiphon stamineus. Five novel highly oxygenated diterpenes, orthosiphols k 1, l 2, m 3, and n 4 and norstaminone a 5, were isolated from the aerial part of orthosiphon stamineus, together with three known. Orthosiphon stamineus introduction orthosiphon stamineus or misai kucing is a herbal plant belongs to a genus in the family of lamiaceae. Java tea is a medicinal plant, native in south east asia malaysia, indonesia, and thailand and some part of tropical australia. Effective antiepileptic drugs aeds are available but have tolerability issues due to their side effects. Hosted by the usgs core science analytics and synthesis. Cosolvent selection for supercritical fluid extraction.
Ingredients java tea orthosiphon spicatus 450 mgcautions do not flush out the urinary system with java tea or any other medication if you are retaining water due to poor heart or kidney function. Professional to supply java teaorthosiphon stamineusextract. For example, the concentration tested is unknown and no mic was determined. Anticancer activity of orthosiphon stamineus against the.
In vitro antibacterial and antioxidant activities of. Orthosiphon stamineus leaf against staphylococcus aureus but the data available are scarce. Evaluation of the genotoxicity of orthosiphon stamineus. Orthosiphon stamineus or misai kucing is one of the unique medicinal herbs which has been reported to exert dynamic pharmacological properties not only traditionally but also scientifically proven. Five novel highly oxygenated diterpenes of orthosiphon s. Orthosiphon stamineus is a traditional herb that is widely grown in tropical areas. Easy to root from cuttings and grows easily from seeds.
Methods dermal papilla cell lines were cultured with medium and ose at. Orthosiphon is a genus of plants in the family lamiaceae native to africa, southern asia and queensland, with one species o. The leaves and stem tips are used to make medicine. Antiapoptotic and antioxidant properties of orthosiphon. Hussin2 1school of pharmacy, university college sedaya international, 56000 kuala lumpur, malaysia 2school of pharmaceutical sciences, universiti sains malaysia, 11800 usm pulau pinang, malaysia. This page was last edited on 10 december 2014, at 00. Ohashi k, bohgaki t, matsubara t, shibuya h 2000 indonesian medicinal plants. Alzheimers disease ad is a chronic neurodegenerative brain disease which is characterized by impairment in cognitive functioning. The bacterial strains were cultured in a nutrient broth merck, germany for 24 h and diluted with sterilised peptone water. Orthosiphon stamineus os is a herb known in ethnomedicine for treating diabetes mellitus dm. Community herbal monograph on orthosiphon stamineus. Hummingbirds, butterflies and bees find this plant attractive.
Orthosiphon aristatus, also known as java tea and cats whiskers is a medicinal herb traditionally used as remedies for various ailments in southeast asia and in europe. Lamiaceae for uti within rationalized modern phytotherapy is based on governmental monographs for formalized drug registration within the traditional use frame by the european medicine agency hmpc monograph, 2016 and the european scientific cooperative on phytotherapy. Orthosiphon aristatus is a plant species in the family of lamiaceae labiatae. Wmc0061 medicinal potentials of orthosiphon stamineus benth. Parts used fragmented dried leaves, tops of stems pharmacopoeial and other monographs bhp 1996g9 bp2001g15 complete german commission eg3 escop 1997i g52. Phytochemical analysis of andrographis paniculata and. Background orthosiphon stamineus benth lamiaceae is a herbaceous. In silico studies displayed a new binding pattern with topoisomerase 1bdna complex in silico studies found to be coherent with in vitro anticancer activity on orthosiphon ac. Lamiaceae synonyms kumis kucing indonesian, malay, orthosiphon aristatus miq.
Preparation and characterization of nano liposomes of. They are herbaceous shrubs which grow to a height of 1. This study sought to prepare nano liposomes of os ethanolic extract in unpurified soybean phospholipids in order to improve its solubility and permeability. Java tea azman ramly flickr,bunga misai kuching orthosiphon stamineus rws photo,bunga misai kuching orthosiphon stamineus rws photo. Orthosiphon stamineus phytochemical and pharmacolo gical research. Here, oe was separated according to polarity and molecular weight, and the antioxidant activity of each component was. Research article effects of a proprietary standardized. The use of leaves from orthosiphon stamineus benth. The leaves are simple, green, and arranged in opposite pairs.
Extract of os has been reported to exhibit comparable antioxidant activity with pure quercetin and synthetic antioxidant, bha akowuah et al. Orthosiphon stamineus leaves, as shown by statistically increased urine volumes in treated animals vs. It appears to be a large source of both rosmarinic acid and methylated flavonoids. Lamiaceae is a medicinal plant found around southeast asia that has been employed as treatments for various diseases. The two general species, orthosiphon stamineus purple and orthosiphon stamineus white are traditionally used to treat diabetes, kidney and urinary disorders, high blood pressure and bone or muscular pain. Composition and antibacterial activity of the essential. In this paper a survey is given of the phytochemical and. All structured data from the file and property namespaces is available under the creative commons cc0 license. Lamiaceae is an asian folklore medicinal plant that has been employed as treatments for various diseases like influenza, inflammation, urinary tract infections, and angiogenesis related conditions like cancer geng et al. Orthosiphon stamineus is an unusual plant for pots, containers or planted out in the garden. The plant can be identified by its white or purple flowers bearing long, protruding stamens that resemble cats whiskers. This study aims to study the in vitro effect of methanol extract of o. However, poor solubility of the active principles limits its medicinal value. Frontiers orthosiphon stamineus leaf extract affects tnf.
Jan 27, 2011 recent studies of orthosiphon stamineus pharmacological profile have revealed antioxidant properties and other potentially useful biological activities thereby lending some scientific support to its use in folk medicine. In the us it may be commonly known as cats whiskers or java tea. Selected metabolites profiling of orthosiphon stamineus benth. Jun 01, 2016 orthosiphon stamineus java tea, cats whiskers is a leaf that is commonly brewed as a tea for a range of purposes, but stated purposes beyond much like the taste of the tea have the tendency to focus on dealing with inflammatory disorders or relieving ailments of the urogenital tract. Final list of references supporting the assessment of. The stem is approximately 54 cm in height at the oldest stage 62 orthosiphon stamineus, the cross sections of different developmental stages of leaves and stems were examined. Flickr brewbooks orthosiphon stamineus cats,pictures of orthosiphon aristatus or orthosiphon stamineus, orthosiphon stamineus.
Os liposomes were prepared by the conventional film method, and were. Polymethoxylated flavones from orthosiphon stamineus leaves. Our ndings suggest that the ethanolic extract of o. Orthosiphon species, cats whiskers, java tea orthosiphon. The plant can be distinguished by its white or purple colored flowers that resembles cat whiskers. Talk with your health provider java tea might have an effect like a water pill or diuretic. In this study, a 1 h nmr based urine metabolomics tool has been used for the first time to identify the metabolic protective mechanism of os in dm using streptozotocin stz induced experimental model in rats. Os extract contains many active compounds that have been shown to possess various pharmacological. Herbal substances binomial scientific name of the plant, including plant part. Orthosiphon stamineus bentham, a medicinal plant in the family lamiaceae, is used to make a well known herbal tea in many countries including malaysia. Direct planting in the field or in the backyard, as is most common, can be done all the year round, but the usual time of planting is at the beginning of the rainy season. Orthosiphon stamineus os popularly known as diuretic agent are traditionally used in folk medicine in the treatment of hyperuricemia, rheumatism, gout, nephritis, nephrolithiasis, urethritis and cystitis.
Orthosiphon stamineus is a malaysian herb also known locally as misai kucing and is widely grown in tropical regions which have high temperatures and yearround rainfall akowuah et al. Antiviral properties of orthosiphon stamineus aqueous. This could increase how much lithium is in the body and result in serious side effects. Medicinal potentials of orthosiphon stamineus benth. Superoxide radical scavenging, hydroxyl radical scavenging, and ferrous ion chelating methods were used to evaluate the antioxidant properties of the extract. Orthosiphon stamineus, better known as misai kucing or cats whiskers by the locals, contained active phenolics compounds such as. Identifying the developmental stages and optimizing the. Os liposomes were prepared by the conventional film method, and were characterized.
Since its establishment as an important cash crop, the herb has been relatively free from any serious insect problems until recently. In addition, it should be noted that the chloroform extract of orthosiphon stamineus leaf is not used traditionally. Orthosiphon stamineus java or cats whiskers is a plant whose leaves make a health tea, used mostly for its antiinflammatory and urinary health properties. Media in category orthosiphon aristatus the following 88 files are in this category, out of 88 total. Effects of a proprietary standardized orthosiphon stamineus. Ya nuad maew, is a widely distributed plant in southeast asia. Study of molecular and genetic diversity of java tea orthosiphon stamineus benth. Orthosiphon stamineus, commonly called java tea thai. Toxicity study of orthosiphon stamineus benth misai.
Professional to supply java teaorthosiphon stamineus. It is also commonly referred as misai kucing malaysian or kumis kucingindonesian which means cat whiskers. Epileptic seizures result from abnormal brain activity and can affect motor, autonomic and sensory function. Abdel sattar a, bankova v, kujumgiev a, galabov a, ignatova a, todorova c, popov s.
Final assessment report on orthosiphon stamineus benth. Jun 14, 2018 orthosiphon stamineus java tea is a leaf that is commonly brewed as a tea for a variety of purposes, but said purposes beyond just liking the taste of the tea tend to revolve around treating inflammatory disorders or treating ailments of the urogenital tract. Cut back old straggly plants to encourage new growth and flowering late in the season. Simultaneous analysis of bioactive markers from orthosiphon. Files are available under licenses specified on their description page. Effect of the orthosiphon stamineus, benth on aminopyrine. Materials and methods uniform plugs of golden shrimp plant, persian shield, and cat whiskers approximately 5, 7, and cm 2. Cats whisker presentation free download as powerpoint presentation. Affordable and search from millions of royalty free images, photos and vectors. Orthosiphon stamineus is one of the traditionally used medicinal plants belonging to lamiaceae family, exhibiting a wide range of pharmacological properties. Orthosiphon stamineus leaf extract protects against ethanolinduced gastropathy in rats. Many studies have shown that orthosiphon stamineus extract oe has antioxidant activity, and we previously reported that oe protects the intestine against injury from a highfat diet.
Pdf diuretic properties of orthosiphon stamineus benth. Antioxidant and toxicity studies of 50% methanolic extract of. The malaysian herb orthosiphon stamineus, is a traditional epilepsy remedy and possesses antiinflammatory, anti. This means it is taken along with lots of fluids to increase urine flow. The agency acknowledges that copies of the underlying works used to produce this monograph were provided for research only with exclusion of any commercial purpose. Orthosiphon stamineus supplement health benefits, dosage. Urinary metabolomics study on the protective role of. Java tea orthosiphon stamineus extract and antihyperglycemic.
Pdf preliminary morphological and anatomical study of. Community herbal monograph on orthosiphon stamineus benth. Traditionally, it is used in folk medicine by preparing tea from the leaves as beverage to improve health and for treatment of kidney, bladder inflammation, gout and diabetes. It features long white or blue flowers with long stamens the cats whiskers over glossy midgreen foliage. Orthosiphon stamineus benth lamiaceae is a herbaceous perennial plant, widely distributed throughout the tropical regions, especially in southeast asia. Orthosiphon stamineus cats whiskers is a popular medicinal herb in southeast asia and currently cultivated in malaysia. Orthosiphon stamineus os is a wellknown herb in south east asia belonging to the lamiaceae family. The product is a traditional herbal medicinal product for use in specified indication exclusively based on longstanding use. Orthosiphon stamineus is an indigenous medicinal plant of southeast asia that has been traditionally used in the treatment of rheumatoid arthritis, gout, and other inflammatory disorders. The plant is a medicinal herb found mainly throughout southern china, the indian subcontinent, south east asia and tropical queensland. Antihyperuricemic and nephroprotective effects of extracts from orthosiphon stamineus in hyperuricemic mice wen. Evidencebased complementary and alternative medicine. Lamiaceae or misai kucing malay for cats whiskers is commonly used as java tea.
Treated as a perennial where hardy and as an annual elsewhere. A simple and facile analytical method was developed using rp hplc with uv detection for the identification and quantitation of bioactive markers present in o. Diuretic properties of orthosiphon stamineus benth authors. However, the molecular mechanism underlying this protective effect of oe was unclear. Is used as a plant for pots, containers or planted out in the garden. Toxicity study of orthosiphon stamineus benth misai kucing on sprague dawley rats chin jin han1, abas hj hussin2, sabariah ismail3 1school of pharmacy, university college sedaya international, 56000 kuala lumpur, malaysia.
Orthosiphon stamineus java tea, cats whiskers is a leaf that is commonly brewed as a tea for a range of purposes, but stated purposes beyond much like the taste of the tea have the tendency to focus on dealing with inflammatory disorders or relieving ailments of the urogenital tract. In this work, the plant compounds were identified from the literature survey and its activity were validated against breast cancer target protein er. Orthosiphon stamineus, java tea, antihypertensive, sinensetin, methylripariochromene a as keywords. The leaves of the plant are used on their own and also in combination with various other herbs. Orthosiphon stamineus health benefits health and welfare. It is known as kumis kucing in indonesia and misai kucing in malaysia, both of which translates to cats whiskers. S college of pharamaceutical sciences,sulur, coimbatore, tamil nadu,india.
Orthosiphon stamineus, een geneeskruid met een diuretische werking. Lambiaceae is an important plant in traditional folk medicine. Directions take 1 capsule at each meal with a large glass of water. Pdf medicinal potentials of orthosiphon stamineus benth.
So far the genotoxicity of orthosiphon stamineus extracts has not been evaluated. Orthosiphon stamineus is one of the popular herbal preparations that is traditionally used, especially as a diuretic or for the elimination of kidney stones. In this study, the essential oils of orthosiphon stamineus benth and ficus deltoidea jack were evaluated for their antibacterial activity against invasive oral pathogens, namely enterococcus faecalis, streptococcus mutans, streptococcus mitis, streptococcus salivarius, aggregatibacter actinomycetemcomitans, porphyromonas gingivalis and fusobacterium nucleatum. Three cultivars of orthosiphon aristatus are distinguished. Highlyoxygenated isopimaranetype diterpenes from orthosiphon stamineus of indonesia and their nitric oxide inhibitory activity. Orthosiphon orthosiphonis folium herbal medicines for. Toxicity study of orthosiphon stamineus benth misai kucing. The leaves of os have traditionally been used in treating in.
The whiteflowered cultivar with reddish stems, petioles and leaf veins appears to possess the best diuretic qualities. It is a popular folk medicine broadly used in southeast asia for the treatment of wide range of diseases and in malaysia, the tea made from o. Awale s, tezuka y, banskota ah, adnyana ik, kadota s. Java tea species family orthosiphon stamineus benth. Cats whisker or in scientific terms called orthosiphon stamineus was originates from south east asia and subtropical australia. Leaves of this plant are used commonly in southeast asia and european countries for herbal tea, well known as java tea. Cuttings are usually planted in shade, with 40 60cm between plants and rows. Page designed through the cooperative efforts of interagency itis teams. Taking java tea might decrease how well the body gets rid of lithium.